Follistatin-344 1 mg Peptide Sciences | TPT0179
Follystatin (FST) is a secret glycoprotein, which was first identified as a follicle stimulating hormone inhibitor in the follicular fluid of the ovary (1, 2). Human follystatin CDNA encodes a protein of 344 amino acids (aa) with a signal sequence of 29 aa, an intolerant atypical TGF-binding domain, three follystatin domains that contain EGF-like and casallic motifs, and a high acid tail of the terminal. Follistatin is a secret protein that binds to TGF-Beta family ligands and regulates their activity by inhibiting their access to signal receptors. Originally, it was discovered as an activin antagonists whose activity suppresses the expression and secretion of FSH (follicle stimulating hormone) hypophysis hormone.
In addition to being a natural antagonist, follystatin can inhibit the activity of other beta ligands of TGF, including BMP-2, -4, -6, -7, Myostatin, GDF-11 and TGF-Beta1. Follistatin is expressed in the pituitary gland, ovaries, endometrial deciduous cells and in some other tissues. Recombinant human follistatin is a 37.8 kDa protein containing 344 amino acids.
|Active ingredient, mg||1|
|1 bottle, ml||10|
|Vials per package, pcs||5|
|Release form||1 bottle, Paking (5 bottles)|